The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Showing 384 of 1002 episodes about AI · Show all
This episode is a special replay from The Generalist Podcast, featuring a conversation with a16z General Partner Martin Casado. Martin has lived through multiple tech waves as a founder, researcher, and investor, and in this discussion he…
a16z co-founder and General Partner Ben Horowitz joins James Norman on the inaugural episode of Vintage x Vintage for a conversation spanning entrepreneurship, investing, hip-hop, and what changes when AI makes building dramatically easier.
a16z's Raghu Raghuram and Guido Appenzeller sit down with Playground Global General Partner and former Intel CEO Pat Gelsinger to discuss the next wave of semiconductor innovation and the physical constraints shaping the AI buildout.
a16z’s Raghu Raghuram sits down with AWS CEO Matt Garman to discuss how AI is reshaping the cloud, from the needs of AI-native startups to infrastructure increasingly designed for agents.
a16z General Partner David George sits down with Armadin founder and CEO Kevin Mandia to discuss what happens to cybersecurity when attackers can operate at machine speed.
a16z Editorial Partner Elena Burger sits down with investing partners Olivia Moore and Josh Elman to unpack the seventh edition of a16z’s Top 100 Consumer AI Apps, including a new dimension this time: what consumers are actually paying for.
a16z General Partner David George joins Jack Altman on Uncapped to make the case that many of the biggest debates in AI are framed the wrong way. Frontier models or open source? Labs or applications? David’s answer is often “and.” With AI…
A16z’s Erik Torenberg sits down with OpenRouter’s Alex Atallah and Replit founder and CEO Amjad Masad to discuss why the future of AI may look less like one all-purpose model and more like an ecosystem of specialized models working…
a16z’s Seema Amble and Elena Burger sit down with Lio co-founder and CEO Vladimir Keil to ask where AI-native startups have an advantage when incumbent software companies already own the customer, the data, and the system of record.
a16z’s Joel de la Garza sits down with DoxxNet founder Barrett Lyon to discuss what it would take to rebuild the internet around privacy, direct communication, and less dependence on centralized intermediaries.
a16z’s David George, Sarah Wang, Alex Immerman, and Santiago Rodriguez unpack 25 key charts from the latest State of Markets presentation, from the scale of the AI infrastructure buildout to what adoption looks like inside companies today.
a16z General Partner Anish Acharya sits down with Assistant Benchmark creator David Pawlan to unpack the sudden explosion of personal AI agents and what it will take for one to become part of everyday life.
a16z’s Ben Horowitz and Martin Casado sit down with TypeSafe AI founder Diogo Almeida to ask a simple question: AI has become remarkably capable, so where is all the automation?
a16z’s Katie Kirsch sits down with Harvey VP of Talent Maggie Landers to discuss what happens inside a company growing at AI speed, and how you preserve culture while adding more than 1,000 employees in a year.
Erik Torenberg sits down with Box CEO Aaron Levie, and a16z’s Martin Casado, and Steven Sinofsky to debate how the AI industry should think about safety, security, and regulation as increasingly capable agents move into the real world.
a16z crypto General Partner Eddy Lazzarin joins Theo Jaffee on MTS to debate the increasingly prominent calls to slow AI development and whether the current safety conversation is conflating very different kinds of risk.
Erik Torenberg sits down with Replit founder and CEO Amjad Masad and Horowitz and Andreessen Academy co-founder and CEO Gagan Biyani to ask what education should look like for a generation growing up with AI.
Ben Horowitz and Erik Torenberg sit down with Gagan Biyani to introduce the Horowitz Andreessen Academy and discuss a bigger question: what should education look like when AI is rapidly changing the skills people need to build, work, and…
a16z Board Partner and former Microsoft Windows president Steven Sinofsky joins Theo Jaffee and Sofia Puccini on MTS to argue that the language we use to describe AI failures is making it harder to understand what’s actually going wrong.
a16z Partner Josh Elman joins Ollie Forsyth on New Economies to discuss the next wave of consumer AI and what separates a product people try once from one that becomes part of their everyday lives.
Databricks co-founder and CEO Ali Ghodsi joins a16z General Partners Martin Casado and Sarah Wang for a conversation about AI risk, recursive self-improvement, cybersecurity, and what’s actually holding back enterprise adoption.
a16z General Partner Jennifer Li sits down with fal co-founder Gorkem Yurtseven and Head of Engineering Batuhan Taskaya to discuss what changes when generative video becomes fast enough to run in real time.
a16z’s Alex Rampell and Joe Schmidt sit down with Lightfield co-founder and CEO Keith Peiris to discuss what it takes to rethink the CRM for an AI-native world, and the unusual pivot that got him there.
Ben Horowitz and Erik Torenberg sit down with OpenAI co-founder and President Greg Brockman to discuss why he believes AI has entered a new phase, what OpenAI’s latest models reveal about the path to AGI, and the safety and security…
World Labs co-founder Justin Johnson joins MTS hosts Theo Jaffee and Sofia Puccini to discuss Atlas, World Labs’ latest world model, and the broader case for AI systems that understand and interact with the physical world.
a16z General Partner Anish Acharya joins Lenny Rachitsky on Lenny’s Podcast to discuss why fears of an AI-driven “permanent underclass” may be misplaced, how AI is changing the way companies operate, and why the opportunity may be less…
a16z’s Matt Perault sits down with General Partner and Speedrun lead Andrew Chen on the a16z AI Policy Brief to explore what “Little Tech” actually looks like at the earliest stages, and why the realities of building a two- or three-person…
a16z’s Jen Kha and David George sit down with Accolade Partners’ Aram Verdiyan to discuss how AI is changing the power law of technology investing, why the largest companies can compound advantages in ways that weren’t possible before, and…
a16z’s Erik Torenberg, Ben Horowitz, and Jennifer Li sit down with Vals founder and CEO Rayan Krishnan to discuss one of AI’s increasingly difficult problems: how do you actually measure whether a model is getting better?
a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark Sellke to discuss how quickly AI’s mathematical capabilities are advancing, what recent results reveal about model reasoning, and what happens when…
MTS host Sophia Dew visits the Open Source AI Summit in San Francisco to ask researchers and founders across the AI stack a central question: can open source prevent AI power from concentrating in the hands of a few companies?
a16z General Partner Julie Yoo joins MTS host Sophia Dew to explain why she believes healthcare could benefit more from AI than almost any other industry, and why decades of slow technology adoption may actually give healthcare an…
Box co-founder and CEO Aaron Levie joins MTS hosts Theo Jaffee and Sofia Puccini to make the case for open-weight AI, unpack the economics of open versus closed models, and explain why he believes more openness could strengthen rather than…
World Labs co-founders Fei-Fei Li, Justin Johnson, and Ben Mildenhall join a16z General Partner Martin Casado to discuss Atlas, their latest world model, and what it reveals about the pursuit of spatial intelligence.
Erik Torenberg is joined by a16z General Partner Alex Rampell and Affirm Co-Founder and CEO Max Levchin for a conversation on 25 years of fintech, from the early days of digital payments to the origins of Affirm and the next generation of…
a16z’s Lisha Li sits down with Daniel Litt, Assistant Professor of Mathematics at the University of Toronto, to unpack AI's rapid progress in mathematics, what today's frontier models can actually do, and what they're still missing about…
a16z’s David George sits down with Gavin Baker to unpack the state of the AI boom, why demand for intelligence may still be dramatically underestimated, and why the outcome doesn't necessarily have to be winner-take-all.
a16z Managing Partner and Head of Global Partnerships Jen Kha joins MTS hosts Theo Jaffee and Sophia Dew to discuss a16z's Machine Age Fund and the investment thesis behind rebuilding the physical infrastructure that powers AI.
Ryan Greenblatt, Chief Scientist at Redwood Research, joins MTS host Theo Jaffee to unpack a new independent investigation into the OpenAI Hugging Face hacking incident and what it reveals about how large groups of AI agents behave when…
Ben Horowitz, Martin Casado, Raghu Raghuram, and Erik Torenberg discuss the launch of a16z's new Machine Age Fund and the infrastructure buildout behind AI, from chips, memory, and networking to power, cooling, and data centers.
a16z General Partners Martin Casado, Sarah Wang, and Matt Bornstein unpack the story of Cursor: how a small, product-obsessed team entered one of the most competitive markets in technology, took on incumbents with seemingly unbeatable…
Anish Acharya joins Jen Kha to break down the next frontier of AI, from the evolving model landscape and open-source AI to why the application layer, and consumer AI in particular, may be entering a new phase.
a16z General Partners Martin Casado and Erik Torenberg are joined by Board Partner Steven Sinofsky to explore what recent breakthroughs in AI and mathematics tell us about where the technology is headed, and whether some of the basic…
Daisy Wolf and Eva Steinman are joined by Engy Ziedan, co-founder and Chief Scientific Officer of Protege, to discuss why medical AI has a measurement problem, and why scoring well on a benchmark doesn't necessarily mean a model is ready…
Martin Casado joins MTS hosts Theo Jaffee and Sophia Dew to unpack where value is actually accruing in AI, why this technology cycle looks fundamentally different from previous waves, and whether the frontier labs will ultimately capture…
a16z's Joel De La Garza is joined by Aaron Zollman, Deputy CISO at Microsoft Gaming, to discuss how security teams can embrace AI agents without losing control.
a16z's Joel De La Garza is joined by Nick Warner of Neo and Max Pollard of Cotool to discuss what happens when cybersecurity tools built to defend against humans and malware suddenly have to contend with AI agents. As frontier models…
a16z General Partner David George is joined by Will Gaybrick, President of Product & Business at Stripe, to discuss how AI is changing the way Stripe builds products, organizes teams, and thinks about the future of internet commerce.…
Elena Burger is joined by a16z's Andy McCall and Joe Schmidt to break down two very different ways AI startups can go to market: the lighthouse and the landgrab. Should founders win a handful of marquee customers whose credibility unlocks…
Anish Acharya is joined by Garry Tan, President and CEO of Y Combinator, for a conversation about how AI is rewriting the startup playbook, why founders should be more ambitious than ever, and what two decades of Silicon Valley booms…
a16z's Joel De La Garza is joined by Emilio Escobar, Chief Information Security Officer at Datadog, to discuss what it takes to secure a company where nearly every employee is using AI and more than 4,000 engineers are working with coding…
Angela Strange and Gabriel Vasquez are joined by Alejandro Maza Ayala, Chief Product & AI Officer at Kavak, to unpack how the Latin American used-car marketplace rebuilt itself around AI agents, with 96% of customer interactions and 95% of…
Joel De La Garza is joined by Dylan Ayrey, co-founder and CEO of Truffle Security, and Feross Aboukhadijeh, founder and CEO of Socket, to discuss one of the biggest shifts happening in cybersecurity: AI models are no longer just finding…
Elena Burger and Matt Bornstein are joined by Simon Mo, co-founder and CEO of Inferact, the open-source inference engine powering many of today's most advanced AI applications. Together, they explore how open-source AI evolved from a…
Theo Jaffee is joined by Joshua Achiam, Chief Futurist at OpenAI, for a conversation on AI cybersecurity, frontier model capabilities, and why he believes society may have already crossed the threshold into an AGI-era without fully…
Sophia Dew and Sofia Puccini are joined by Ruby Thelot, designer, artist, cyberethnographer, professor at NYU, and founder of 13101401, for a wide-ranging conversation about internet culture, AI, digital communities, and how technology is…
Sarah Wang and Kimberly Tan are joined by Jesse Zhang and Ashwin Sreenivas, co-founders of Decagon, to discuss the evolution of enterprise AI agents, why the company increasingly relies on open-source models, and how it is helping some of…
Alex Rampell and Olivia Moore speak with Lassie cofounders Steijn Pelle and Frédéric Renken about bringing AI to one of the most overlooked parts of the economy: small businesses.
Justine Moore, partner at Andreessen Horowitz, joins New Economies to explore the rapid evolution of generative media and why AI-native content is reaching an inflection point. They discuss the rise of AI micro-dramas, how creators are…
Last week, World Labs announced its acquisition of SceniX, bringing together two teams working on one of AI's biggest unsolved problems: how to give machines a true understanding of the physical world.
Steven Sinofsky joins Theo Jaffee and Sofia Puccini for a conversation on AI regulation, open-source models, and what history can teach us about technological revolutions. Drawing on decades of experience leading products at Microsoft…
Ben Horowitz joins Theo Jaffee and Sofia Puccini to discuss one of the biggest debates in AI today: the future of open-source models. They examine the growing push to restrict open models, why Ben believes open source is critical for…
Sriram Krishnan joins Theo Jaffee and Sofia Puccini just after concluding his tenure as Senior White House Policy Advisor on AI to discuss one of the biggest weeks yet for open-source AI. They unpack the rapid release of models including…
Travis Kalanick joins TBPN to discuss Atoms, his vision for industrial AI, and why he believes the biggest opportunities in AI lie beyond software.
Travis Kalanick, Ben Horowitz, and Erik Torenberg reunite to reflect on Uber's early days, the investment that almost happened, and why Kalanick believes the next great technology opportunity lies beyond software.
Applied Intuition has spent the past decade building the software that powers intelligent machines, from passenger vehicles and trucks to defense systems, mining equipment, and industrial robots.
As governments weigh new restrictions on frontier AI models, one question is becoming increasingly important: what role should open source play in the future of artificial intelligence?
Recorded live at the New Media Summit, Erik Torenberg sits down with Replit founder and CEO Amjad Masad to discuss founder-led storytelling, building in public, and the role of media in company building.
As part of our summer replay series, we're revisiting one of our most-discussed conversations from the past year.
As part of our summer replay series, we're revisiting one of our favorite conversations on the future of AI infrastructure.
As part of our summer replay series, we're revisiting one of the standout conversations from Runtime, a16z's conference on AI infrastructure and the future of computing.
As part of our summer replay series, we're revisiting one of our favorite conversations from the past year.
Seema Amble, Steven Sinofsky, and Elena Burger unpack one of the biggest questions facing enterprise software: what happens when AI agents become the primary users of software instead of humans?
Rick Rubin joins Marc Andreessen, Ben Horowitz, Anjney Midha, and Erik Torenberg to discuss creativity, artificial intelligence, and his book The Way of Code, which reimagines the Tao Te Ching for the age of AI.
Yoko Li speaks with Luma's Head of Applied Research Matt Tancik and Phota Labs cofounder and CTO Zach Xia about how AI is changing creativity, photography, and the tools people use to make art.
Marc Andreessen joins CSIS's Navin Girishankar for a wide-ranging conversation on artificial intelligence, productivity growth, industrial policy, and America's technological future.
Kevin Weil, the previous CPO & Vice President of Science at OpenAI, joins Speedrun to discuss the future of AI, scientific discovery, and startup building.
Michael Malice sits down with Marc Andreessen to discuss artificial intelligence, technological progress, economic growth, and the future of human flourishing.
Anish Acharya speaks with Microsoft VP of Design John Maeda and Impeccable founder and CEO Paul Bakaus about how AI is changing the practice of design.
Anish Acharya sits down with Josh Elman to discuss the future of consumer technology and Josh's decision to join a16z.
Jack Altman joins Speedrun to discuss product-market fit, customer feedback, hiring, fundraising, and the realities of building an enduring company.
Yoko Li and Justine Moore speak with Ideogram founder and CEO Mohammad Norouzi about image generation models, design workflows, and the evolving relationship between AI and creative work.
Theo Jaffee speaks with Samo Burja, founder of Bismarck Analysis, about AI, industrial capacity, economic growth, and the institutions that shape civilization.
Erin Price-Wright speaks with Alex Modon, cofounder and CEO at Unlimited Industries, and Davide Asnaghi, CEO at Diode Computers, about how AI is moving from software into the physical world. They discuss automating construction and…
Wyatt Thomson of OpenAI speaks with economists Tyler Cowen and Alex Tabarrok about AI, labor markets, and the future of economic growth.
Erik Torenberg speaks with tech analyst Benedict Evans about the current state of AI, what has changed over the past year, and which questions remain unanswered.
Sarah Wang speaks with Exa cofounder and CEO Will Bryk about building search infrastructure for the AI era.
Martin Casado speaks with George Fraser, cofounder and CEO of Fivetran, about the future of data infrastructure in the age of AI.
Theo Jaffee speaks with Steven Sinofsky about the next generation of personal computing and the growing role of AI-native hardware.
Anish Acharya and Olivia Moore speak with Pablo Palafox and Luis Paarup about the challenges of deploying AI agents in operationally complex industries.
David George, General Partner at a16z, and David Clark, CIO at VenCap, discuss how AI is reshaping venture capital and the technology industry itself. They examine why today’s AI companies are scaling faster than any previous generation of…
Angela Strange speaks with Dileep Thazhmon, founder and CEO of Jeeves, about building a global financial operating system for enterprises across Latin America using stablecoins and AI.
Originally aired on MTS segment, Monetary Matters, Jack Farley and Max Wiethe speak with Ara Kharazian, Lead Economist at Ramp, about what real business spending data says about AI adoption, why the “SaaSpocalypse” narrative is overblown…
Clem Delangue joins MTS to discuss the global open-source AI landscape, the current large language model bubble, and the future of consumer robotics.
Marc Andreessen joins Joe Rogan for a conversation on AI, politics, technology, and the future of American society. They discuss how artificial intelligence is rapidly moving from novelty to infrastructure, and why Andreessen believes its…
David Ulevitch speaks with Col. Jeffrey Glover and Rahul Sidhu about how AI, drones, and sensor networks are reshaping public safety and what it takes to bring new technology into law enforcement at scale. As departments face staffing…
Sophia Dew and Binji Pande speak with Vitalik Buterin about technology, human agency, and how the internet is changing the way people think, build, and relate to the world around them. Drawing from his writings and personal reflections…
Ben Horowitz shares lessons from building and scaling companies, drawing on his experience as a founder and CEO. He explains why a founder’s primary responsibility comes down to one thing: delivering the right product at the right time.
Erin Price-Wright speaks with Turner Caldwell and Drew Baglino about what it will take to close America's critical minerals gap and modernize the power infrastructure that underpins the AI economy. With the US more than 50 years behind…
Erik Torenberg speaks with Marc Andreessen about the state of AI, media, and the broader cultural and economic shifts shaping the internet. They discuss how narratives around AI, from fear to hype, are influencing public perception, and…
Katherine Boyle speaks with Sarah Rogers, Under Secretary for Public Diplomacy, about the intersection of AI, free speech, and global information systems. They discuss how major technological shifts, from the printing press to the internet…
Theo Jaffee speaks with Balaji Srinivasan and Taylor Lorenz about how AI is reshaping media, trust, and online communication. Building on prior public disagreements between the two, the conversation revisits core tensions around media…
Elena Burger speaks with Joe Schmidt, partner on the enterprise team at a16z, about the future of enterprise software in the age of AI. Using Workday as a case study, they discuss why many of today’s most important enterprise systems feel…
This interview with Stripe cofounders John and Patrick Collison originally aired on TBPN. They discuss Stripe's 34% growth and new employee tender offer, how agent commerce and stablecoins may require high-throughput blockchains built for…
Anjney Midha, founder of AMP PBC, speaks with Ben Horowitz, cofounder of a16z, about how venture capital changed from a small, relationship-driven business into a scalable system for backing new technology companies. They discuss network…
Steven Sinofsky, board partner at a16z, Aaron Levie, CEO of Box, and Martin Casado, general partner at a16z, discuss the reality of AI inside enterprises. They cover the gap between Silicon Valley and the rest of the world, why most AI…
Erik Torenberg speaks with Martin Shkreli, American investor and businessman, about how he sees the AI landscape, from OpenAI to Anthropic, and what actually matters beyond the hype. They also talk through the future of computing, the…
Erik Torenberg and Theo Jaffee speak with Balaji Srinivasan, angel investor, entrepreneur, and author of The Network State, about how AI is transforming media, eroding trust, and reshaping how information is created and verified. They…
Matt Bornstein speaks with Scott Chacon, cofounder of GitHub and CEO of GitButler, about why Git's user interface has barely changed since 2005, how GitButler is rethinking version control for both humans and AI agents, and what the "next…
This episode originally aired on The Kevin Rose Show. Kevin Rose speaks with Anish Acharya, general partner at a16z, about how AI is rewriting the rules of consumer software, the defensibility of network effects in a world where anyone can…
Waymo is now delivering hundreds of thousands of fully autonomous rides each week — but getting there required more than better models. It meant building a complete system for training, evaluating, and deploying a driver in the real world.
Erik Torenberg and Anish Acharya, general partners at a16z, speak with signüll about how technology reshapes culture, relationships, and the products we build. The conversation covers tacit knowledge versus intellectual knowledge, dating…
Jack Neel speaks with Amjad Masad, CEO at Replit, about how AI is making it easier than ever to build and ship software without a technical background. They discuss Replit's rise from a browser-based coding tool to a platform generating…
Recorded live at the a16z Fintech Connect conference in Deer Valley, Alex Rampell speaks with Ben Horowitz, cofounder and general partner at a16z, about how AI has rewritten the fundamental rules of software competition, why crypto…
Katherine Boyle and Sarah Wang speak with Jesse Genet, a startup founder and family builder, about building 11 AI agents while homeschooling four young children. Jesse runs agents across roles ranging from coding to curriculum planning to…
Eddy Lazzarin speaks with Vitalik Buterin, founder of Ethereum, and Guillaume Verdon, founder and CEO of Extropic, about whether AI progress can or should be steered, the risks of concentrated power, and what open source and…
Erik Torenberg, Steve Sinofsky, and Martin Casado speak to Aaron Levie, CEO at Box, about what happens to enterprise software when agents become the primary users. They discuss why coding agents succeed where other knowledge work agents…
a16z general partner Erik Torenberg speaks with Balaji Srinivasan, angel investor and entrepreneur, about why AI simultaneously reduces the cost of creation and increases the cost of verification, and what that tension means for the shape…
Anish Acharya speaks with Peter Yang, creator and product lead at Roblox, about how personal AI agents are replacing the apps we open every day, why coding agents feel like slot machines, and what happens when the cost of building software…
This episode originally aired on the Latent Space Podcast. swyx and Alessio Fanelli speak with Marc Andreessen about the arc of AI from its origins in 1943 to today's breakthroughs in reasoning, coding agents, and self-improvement. They…
a16z's Ben Horowitz and Erik Torenberg speak with Alex Blania, cofounder and CEO of Tools for Humanity, World, and cofounder of Merge Labs. World is building the largest real human network, a proof-of-human layer for the AI era. They cover…
David Haber speaks with Owen Jennings, executive officer and business lead at Block, about how the company rebuilt itself around AI agents, small squads, and internal tools like Goose and Builder Bot after restructuring more than 40% of…
This episode originally aired on The Twenty Minute VC with Harry Stebbings. Marc Andreessen explains why learning from past investment mistakes can be a trap, shares his framework for evaluating founder greatness through IQ, courage, and…
A new paper, “Some Simple Economics of AGI,” is making the rounds—Web3 with a16z we sat down with author Christian Catalini (MIT Crypto Economics Lab) and Eddy Lazzarin (CTO of a16z crypto), in conversation with Robert Hackett, to unpack…
Erik Torenberg sits down with Jacob Helberg to discuss AI, manufacturing, supply chains, and the new geopolitics of technology. Drawing on themes from Helberg’s book The Wires of War, they explore why hardware, industrial capacity, and…
Vishal Misra returns to explain his latest research on how LLMs actually work under the hood. He walks through experiments showing that transformers update their predictions in a precise, mathematically predictable way as they process new…
In this episode, originally aired on Big Technology Podcast, Olivia Moore discusses whether AI startups can compete with the big chatbots, why American sentiment toward AI is so negative, and what she learned from giving LLMs personality…
This conversation with Emil Michael, undersecretary of defense for research and engineering and acting director of the Defense Innovation Unit, was recorded at the a16z American Dynamism Summit in Washington, D.C. Michael walks through how…
This conversation with Alex Karp, cofounder and CEO of Palantir, was recorded at the a16z American Dynamism Summit in Washington, D.C. Karp discusses the role of technology in modern warfare, Silicon Valley's obligations to national…
Anish Acharya speaks with Olivia Moore about the latest edition of the a16z Top 100 AI Apps report. They cover why ChatGPT is still 30 times bigger than Claude on web, how the three major platforms are specializing for different users…
Alex Rampell and Erik Torenberg speak with Mike Cannon-Brookes, cofounder and CEO of Atlassian, about how to make sense of the SaaS selloff, why not all software companies face the same AI-driven risks, and how Atlassian is thinking about…
In this conversation, previously aired on TBPN, John Coogan and Jordi Hays speak with Ben Thompson, founder of Stratechery, about his essay "Anthropic and Alignment" and the broader collision between AI power and state power that the…
a16z general partner Julie Yoo talks with Nikhil Buduma, CEO and cofounder of Ambience Healthcare, to discuss how AI is transforming clinical workflows. They cover the early days of deep learning, why Ambience started by running a medical…
Moonshots host Peter Diamandis speaks with Ben Horowitz, cofounder and general partner at a16z, alongside regular cohosts Salim Ismail, Dave Blundin, and Dr. Alexander Wissner-Gross, about whether AI can or should be paused, what happened…
Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the MongoDB and Ruby decisions Stripe still lives with 15 years later…
a16z's Martin Casado and Sarah Wang join Latent Space hosts Alessio Fanelli and Swyx to discuss what makes this AI investment cycle unlike anything in the history of venture capital. They cover why the lines between venture and growth…
a16z's Angela Strange and Gabriel Vasquez speak with Carlos García Ottati, founder and CEO of Kavak, about building Latin America's largest online used car marketplace across Mexico, Brazil, Chile, Argentina, and the Middle East. They…
In this episode from 20VC, Harry Stebbings talks with Anish Acharya, general partner at a16z, about the future of SaaS in an AI world. Anish argues that software is completely oversold and that the general story about vibe coding…
Cisco president and CPO Jeetu Patel speaks with a16z cofounder Marc Andreessen about why AI may finally break a 50-year productivity slump—and what's at stake if America doesn't win the race. They discuss where value will accrue in the AI…
a16z Head of Investor Relations Jen Kha speaks with general partner David George about the state of AI and private technology markets. David shares data on why AI companies are growing 2.5x faster than traditional software while spending…
Christopher Mims and Tim Higgins of the Wall Street Journal sit down with a16z General Partner Martin Casado on WSJ’s Bold Names to ask whether the AI spending boom is a bubble waiting to burst. Martin explains why the fundamentals differ…
a16z general partner David Haber spoke with Goldman Sachs CEO David Solomon and a16z cofounder Ben Horowitz on the current macro environment, enterprise AI adoption, and crypto and AI policy. Solomon describes what he calls the "sweetest…
Netlify's CEO, Matt Biilmann, reveals a seismic shift nobody saw coming: 16,000 daily signups—five times last year's rate—and 96% aren't coming from AI coding tools. They're everyday people accidentally building React apps through ChatGPT…
Recently, Marc Andreessen joined Lenny Rachitsky on Lenny's Podcast. They talked about why 2025 may be the most significant year in tech history, how AI is reshaping the future of product managers, designers, and engineers, and what…
Out-of-Pocket is a healthcare education company founded by Nikhil Krishnan that helps people understand how healthcare works and how to navigate it in practice. In this episode, a16z investing partner Jay Rughani and Nikhil discuss why…
In this episode, Jen Kha, Head of Investor Relations, and David George, General Partner, discuss how late-stage private markets are evolving as AI reshapes scale, capital intensity, and growth timelines. They explain why AI-driven…
Mintlify is a documentation platform built by cofounders Han Wang and Hahnbee Lee to help teams create and maintain developer docs. In this episode, Andreessen Horowitz general partners Jennifer Li and Yoko Li speak with Han and Hahnbee…
Inferact is a new AI infrastructure company founded by the creators and core maintainers of vLLM. Its mission is to build a universal, open-source inference layer that makes large AI models faster, cheaper, and more reliable to run across…
In this feed drop from The Six Five Pod, a16z General Partner Martin Casado discusses how AI is changing infrastructure, software, and enterprise purchasing. He explains why current constraints are driven less by technical limits and more…
Sourcegraph's CTO just revealed why 90% of his code now comes from agents—and why the Chinese models powering America's AI future should terrify Washington. While Silicon Valley obsesses over AGI apocalypse scenarios, Beyang Liu's team…
The a16z AI Apps team outlines how they are thinking about the AI application cycle and why they believe it represents the largest and fastest product shift in software to date. The conversation places AI in the context of prior platform…
The Stanford PhD who built DSPy thought he was just creating better prompts—until he realized he'd accidentally invented a new paradigm that makes LLMs actually programmable.
AI is changing how companies are built and how venture firms operate, forcing faster decisions, clearer judgment, and new ways of working.
In this feed drop from Uncapped, Jack Altman sits down with a16z co-founder Ben Horowitz to unpack the founding bet behind Andreessen Horowitz. VC should be a better product for entrepreneurs, built on real operating experience, real…
In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Keycard to manage fleets of agents.
a16z co-founder and General Partner Marc Andreessen joins an AMA-style conversation to explain why AI is the largest technology shift he has experienced, how the cost of intelligence is collapsing, and why the market still feels early…
Originally published in June 2023, this conversation features a16z cofounder Marc Andreessen following the release of his nearly 7,000-word essay arguing that AI does not threaten our humanity. In a wide-ranging discussion with a16z…
As 2025 comes to a close, consumer AI is entering a new phase. A small number of products now dominate everyday use, multimodal models have unlocked entirely new creative workflows, and the big labs have pushed aggressively into consumer…
AI is moving into the physical economy.
Voice is becoming one of the fastest paths for AI to do real work, especially in regulated environments where accuracy and compliance matter. In this episode, we look at voice agents replacing and augmenting phone-based workflows, what…
AI is becoming the orchestration layer inside the enterprise.
AI is moving from chat to action.
In this episode, we’re sharing a conversation with David George, General Partner at a16z on the firm’s growth investing team. David has been involved in backing many of the defining companies of this era and is now investing behind a new…
Ryo Lu spent years watching his designs die in meetings. Then he discovered the tool that lets designers ship code at the speed of thought: Cursor, the company where Ryo is now Head of Design. In this episode, a16z General Partner Jennifer…
AI is reshaping the tech landscape, but a big question remains: is this just another platform shift, or something closer to electricity or computing in scale and impact? Some industries may be transformed. Others may barely feel it. Tech…
Originally published on the a16z Infra podcast. We're resurfacing it here for our main feed audience.
Naveen Rao is cofounder and CEO of Unconventional AI, an AI chip startup building analog computing systems designed specifically for intelligence. Previously, Naveen led AI at Databricks and founded two successful companies: Mosaic (cloud…
Fei-Fei Li is a Stanford professor, co-director of Stanford Institute for Human-Centered Artificial Intelligence, and co-founder of World Labs. She created ImageNet, the dataset that sparked the deep learning revolution.
Recently, a16z General Partner Anish Acharya joined Ollie Forsyth on NEW ECONOMIES. They talked about why consumer tech is surging again, how AI is enabling 100M-user products at unprecedented speed, and what founders need to understand…
a16z General Partners David Haber, Alex Rampell, and Erik Torenberg discuss why 19 out of 20 AI startups building the same thing will die - and why the survivor might charge $20,000 for what used to cost $20.
Russ Fradin sold his first company for $300M. He’s back in the arena with Larridin, helping companies measure just how successful their AI actually is.
In this episode, a16z GP Martin Casado sits down with Sherwin Wu, Head of Engineering for the OpenAI Platform, to break down how OpenAI organizes its platform across models, pricing, and infrastructure, and how it is shifting from a single…
Ben Horowitz reveals why the US already lost the AI culture war to China—and it wasn't the technology that failed. While Biden's team played Manhattan Project with closed models, Chinese developers quietly captured the open-source…
Half a billion people can access the world’s best AI on their phone. So why are most using it to write emails while only some are using it to build empires?
Epoch AI researchers reveal why Anthropic might beat everyone to the first gigawatt datacenter, why AI could solve the Riemann hypothesis in 5 years, and what 30% GDP growth actually looks like. They explain why "energy bottlenecks" are…
Emmett Shear, founder of Twitch and former OpenAI interim CEO, challenges the fundamental assumptions driving AGI development. In this conversation with Erik Torenberg and Séb Krier, Shear argues that the entire "control and steering"…
Two venture capitalists dissect why biotech burns billions while China runs trials in weeks—and why the next Genentech won't look anything like the last one. Elliot Hershberg reveals the "three horsemen" strangling drug development as…
Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, they have long been laying the groundwork for the innovations transforming industries today.
Grant Lee was told Gamma was "the worst idea ever heard" by an investor who hung up mid-Zoom—yet he built it to 100 million users and $100M ARR without spending a dollar on advertising.
When four MIT grads decided to build a code editor while everyone else was building AI agents, they created the fastest-growing developer tool ever built.
Adam D’Angelo (Quora/Poe) thinks we're 5 years from automating remote work. Amjad Masad (Replit) thinks we're brute-forcing intelligence without understanding it.
Priscilla Chan and Mark Zuckerberg join a16z’s Ben Horowitz, Erik Torenberg, and Vineeta Agarwala to share how the Chan Zuckerberg Initiative is building the computational tools that will accelerate the cure, prevention, and management of…
Eugenia Kuyda, CEO of Wabi and AI pioneer behind Replika, joins Erik, Anish, and Justine to reveal how personal software will transform from a developer monopoly to a creative medium for all. She exposes why command-line AI interfaces are…
ElevenLabs CEO and co‑founder Mati Staniszewski joins Jennifer Li to explain how the team ships research‑grade AI at lightning speed—from text‑to‑speech and fully licensed AI music to real‑time voice agents—and why voice is the next…
David Sacks, White House AI and Crypto Czar, joins Marc, Ben, and Erik to explore what's really happening inside the Trump administration's AI and crypto strategy. They expose the regulatory capture playbook being pushed by certain AI…
As global tensions rise, AI and autonomy are transforming how nations prepare for conflict.
In this closing keynote from a16z’s Runtime conference, General Partner Erik Torenberg speaks with our firm’s cofounders, Marc Andreessen and Ben Horowitz on highlights from throughout the conference, the current state of LLM capabilities…
In this conversation from a16z’s Runtime conference, Gavin Baker, Managing Partner and CIO of Atreides Management, joins David George, General Partner at a16z, to unpack the macro view of AI: the trillion-dollar data center buildout, the…
AI isn’t just changing software, it’s causing the biggest buildout of physical infrastructure in modern history.
Google DeepMind’s new image model Nano Banana took the internet by storm.
From Netscape to VMware, Raghu Raghuram has been at the center of nearly every major inflection point in enterprise technology.
Amjad Masad, founder and CEO of Replit, joins a16z’s Marc Andreessen and Erik Torenberg to discuss the new world of AI agents, the future of programming, and how software itself is beginning to build software.
In this episode, a16z's Anish Acharya joins Kevin Rose for an in-depth, fast-paced conversation on the rebirth of consumer technology, and how AI is reshaping what it means to build, invest, and create.
Augusto Marietti, CEO and cofounder of Kong, has one of the most remarkable founder stories in Silicon Valley history.
Reid Hoffman has been at the center of every major tech shift, from co-founding LinkedIn and helping build PayPal to investing early in OpenAI. In this conversation, he looks ahead to the next transformation: how artificial intelligence…
From politics to technology to real estate, Keith Rabois has bold predictions for America’s next decade.
Ben Horowitz founded Loudcloud in the middle of the dot-com bust and sold it for $1.6 billion, then led Andreessen Horowitz from its founding to $46 billion in committed capital. Ali Ghodsi co-founded Databricks, stepped in as CEO during a…
Nathan Labenz is one of the clearest voices analyzing where AI is headed, pairing sharp technical analysis with his years of work on The Cognitive Revolution.
From GPT-1 to GPT-5, LLMs have made tremendous progress in modeling human language. But can they go beyond that to make new discoveries and move the needle on scientific progress?
Sam Altman has led OpenAI from its founding as a research nonprofit in 2015 to becoming the most valuable startup in the world ten years later.
From high-speed rail to electric cars to batteries to AI, it’s clear that China can operate with incredible speed at massive scale. Can the US still compete?
Scaling laws took us from GPT-1 to GPT-5 Pro. But in order to crack physics, we’ll need a different approach.
What comes after vibe coding? Maybe vibe researching.
Should the US put a price on H-1B visas, or would that block the flow of new talent? Are AI coding agents actually making teams way more productive, or is it just hype? And in the AI platform shift, will the big winners be incumbents or…
Dr. Jay Bhattacharya is one of the country’s top medical experts and a 24-year professor of medicine at Stanford. After being censored and deplatformed during COVID for his role in opposing harsh lockdowns, he was appointed Director of the…
Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the global chip race.
The web is unhealthy, and AI agents are about to rewrite how we shop.
OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software?
Why do some consumer products explode into networks that reshape the internet, while others fade away?
What happens when AI collides with salesmanship, streaming-era sports, and healthcare?
Who’s speaking up for startups in Washington, D.C.?
Stainless founder Alex Rattray joins a16z partner Jennifer Li to talk about the future of APIs, SDKs, and the rise of MCP (Model Context Protocol). Drawing on his experience at Stripe—where he helped redesign API docs and built…
Jack Altman sits down with Martin Casado, General Partner at a16z, to unpack the shifting dynamics of venture capital and why media matters more than ever. They cover a16z’s evolution from generalists to specialized platforms, the rise of…
In this interview from the 20VC podcast, Martin Casado (a16z General Partner) joins Harry Stebbings to unpack the state of AI, the rise of coding models, the future of open vs. closed source, and how value is shifting across the stack.
What are real consumers actually doing with AI today?
What exactly is an AI agent, and how will agents change the way we work?
Marc Andreessen, cofounder Andreessen Horowitz, joins the Hermitix podcast for a conversation on AI, accelerationism, energy, and the future.
Housing and healthcare make up nearly half of household spending, yet both sectors are riddled with inefficiency and rising costs.
The AI hardware race is heating up, and NVIDIA is still far ahead. What will it take to close the gap?
Genie 3 can generate fully interactive, persistent worlds from just text, in real time.
a16z General Partners Martin Casado and Anjney Midha join Erik Torenberg to unpack one of the most dramatic shifts in tech policy in recent memory: the move from “pause AI” to “win the AI race.”
a16z partners Olivia and Justine Moore unpack the latest in consumer AI including:
There’s been a wave of M&A deals lately - Meta and Scale, Windsurf and Google - and a lot of it points to something bigger: how regulation, capital, and innovation are colliding in 2025.
In this episode, Marc Andreessen joins TBPN for an unfiltered conversation spanning everything from ads in LLMs to why Apple’s AI strategy may be risky for anyone not named Apple.
ChatGPT-5 just launched, marking a major milestone for OpenAI and the entire AI ecosystem.
In this episode, Erik Torenberg is joined in the studio by Dwarkesh Patel and Noah Smith to explore one of the biggest questions in tech: what exactly is artificial general intelligence (AGI), and how close are we to achieving it?
What happens when AI starts generating content for everyone—and no one wants to watch it?
a16z General Partners Erik Torenberg and Martin Casado sit down with technologist and investor Balaji Srinivasan to explore how the metaphors we use to describe AI—whether as god, swarm, tool, or oracle—reveal as much about us as they do…
It can take more than 15 years to permit and build a new mine in the United States - yet nearly every modern technology we rely on, from smartphones to fighter jets to AI data centers, depends on a steady supply of critical minerals.
Is AI the Fourth Pillar of Infrastructure?
In this episode, a16z General Partner Martin Casado sits down with Box cofounder and CEO Aaron Levie to talk about how AI is changing not just software, but the structure and speed of work itself.
This week on the a16z Podcast, we're sharing a feed drop from Impact Theory with Tom Bilyeu, featuring a wide-ranging conversation with a16z cofounder Ben Horowitz.
Taken from the AI + a16z podcast, Arcjet CEO David Mytton sits down with a16z partner Joel de la Garza to discuss the increasing complexity of managing who can access websites, and other web apps, and what they can do there. A primary…
In this episode of ‘This Week in Consumer’, a16z General Partners Anish Acharya and Erik Torenberg are joined by Steven Sinofsky - Board Partner at a16z and former President of Microsoft’s Windows division - for a deep dive on how today’s…
What if virality wasn’t a tactic — but the entire product?
In this episode, general partner Chris Dixon joins economist and author Tyler Cowen to explore the themes behind Chris’s book, Read, Write, Own: Building the Next Era of the Internet.
In this episode, a16z general partner Bryan Kim joins TBPN hosts John Coogan and Jordi Hays to discuss the recent launch of Cluely , a consumer AI product. The conversation covers early traction, evaluating distribution and momentum, and…
How is AI actually being used in classrooms today? Are teachers adopting it, or resisting it? And could software eventually replace traditional instruction entirely?
Things in consumer AI are moving fast. In this episode, Justine and Olivia Moore, investing partners (and identical twins!) at a16z, break down what’s real, what’s overhyped, and what’s next across the consumer AI space. They cover:
In this episode Jack Altman, CEO of Lattice and host of Uncapped, interviews Marc Andreessen on how venture capital is evolving — from small seed funds to billion-dollar barbell strategies — and why today’s most important tech companies…
In this episode, a16z General Partner Erik Torenberg is joined by the a16z Consumer team—General Partner Anish Acharya and Partners Olivia Moore, Justine Moore, and Bryan Kim—for a conversation on the current state (and future) of consumer…
What if the next leap in artificial intelligence isn’t about better language—but better understanding of space?
What happens when two of the biggest tech waves—AI and crypto—start to converge?
In this episode a16z co-founders Marc Andreessen and Ben Horowitz sit down with legendary music producer and bestselling author Rick Rubin to explore the origin of his unexpected new creation: "The Way of Code"*
AI’s breakout moment is here - but where is the real value accruing, and what’s just hype?
What happens when AI stops being just infrastructure—and becomes a matter of national identity and global power?
What exactly is an AI agent — and does anyone actually agree?
Business Process Outsourcing (BPO) is a $300 billion industry powering the back- and front-office operations of the world’s largest companies.
Today on the a16z Podcast, we’re sharing Marc Andreessen’s recent appearance on TBPN.
Are we nearing the end of the smartphone era?
War has always been shaped by technology—from steel and gunpowder to GPS and nuclear weapons. But the decisive technologies of tomorrow aren’t coming—they’re already here.
This month, a16z’s Consumer team released the fourth edition of the GenAI 100 — a data-driven ranking of the top 50 AI-first web products and mobile apps, based on unique monthly visits and active users.
The global race for AI leadership is no longer just about companies—it’s about nations. AI isn’t just computing infrastructure; it’s cultural infrastructure, economic strategy, and national security all rolled into one.
AI voice technology has been around for years — think Siri or Alexa — but the magic has been missing. That’s changing, and quickly!
Henry Ward, cofounder and CEO of Carta, has spent over a decade scaling his company from an early-stage startup to a 2,000-person industry leader. In this a16z Speedrun conversation with Games partner Josh Lu, Henry shares hard-earned…
Being a creator in 2025 is tough—but building for creators is even harder. Perhaps no one understands this conundrum better than Scott Belsky. As the founder of Behance, a longtime executive at Adobe, and an advisor to companies like…
Technology doesn’t grow in isolation—it evolves in waves. Just as mobile, cloud, and SaaS shaped the internet of the past 20 years, so too could crypto, AI, and new hardware usher in an era of the internet that’s pro-innovation…
Two words have caught the Internet by storm. DeepSeek.
How is AI reshaping modern warfare?
Intelligent automation is transforming industries by tackling messy, unstructured workflows that traditional Robotic Process Automation (RPA) couldn’t handle. In this episode, a16z partner Kimberly Tan discusses the shift from rigid RPA…
