Connect Amazon Bedrock AgentCore to cross-account knowledge bases

To connect Amazon Bedrock AgentCore agents in one AWS account to knowledge bases in another account using Amazon Redshift Serverless, with two orchestration variants: a code-based Strands agent and a declarative AgentCore harness, without copying source data across accounts.

The post covers architecture, flow, and selection criteria for the two generally available AgentCore orchestration models.

Models used include Amazon Nova Pro and Claude Haiku 4.5.

The solution relies on cross-account IAM roles and AWS STS to assume role in the knowledge base account and call RetrieveAndGenerate.

The linked GitHub sample provides deployment procedures for both variants.

The post also advises on when to use a simpler approach versus an agent for cross-account queries.